REVIEW ARTICLE AMPA● the p tAA.nmtrie L-glutamate o aptic locus" sufficient to induce ltp but is a nec facto and may be ed in he conversion sis has np nd th eral different Ca"-sen mwhichis h act ve Thishas ed to the p ha f me ence previous Dansie se to lipid-d notypic hippo mpal c hi"naectcdby ated in an NMDA cptordepSnd mbi kinas (PKA Ithas been ctiv ost-translational modificatio both esis inhibito up to 3 n of K (e) pses that have vity that m 6 vcin.which p ts the on o is acti togethe sults su t tha and a pe but fo the first hours nding LTP2 in the tior of the atal are up.or do nregulated du ationofaciP s of PKC ity has b and occlu experiments dic ation sing the pos ibility that cle wit (NCAMs),may contribute to synaptic remodelling in LTP. NATURE·VOL361·7 JANUARY1993 0193 ing Group © 1993 NaturePublishingGroup