The Life Cycle of Schistosoma spp (the causative agent of schistosomiasis) Worms reach sexual maturity in veins of abdominal cavity, females produce eggs, eggs enter intestinal tract or bladde mmature worm enters the blood stream and eventually ends up in veins near the testine or bladder Eggs passed in urine Cercariae leave snail or feces into fresh water penetrate skin of human who is in water Miracidium hatches from egg, infects first intermediate host (a snail) (Parasites and Parasitological Resources)