242SECT|○N‖· WHAT TO D○W| TH THE| NFORMAT|ON TABLE 9.2 Pharmacologic Adjuvants for Smoking Cessation Agent( Brands)Advantages Disadvantages IcotIne OTC Proper use required gum Flexible dosing Frequent use required Nicorette) Fast nicotine delivery No food or drink 15 min May delay weight gain before use Possible jaw pain, mouth soreness,dyspepsia, h CUps A void use with dental roblems or temporomandibular joint syndrome cotone OTC Frequent dosing required lozenge Flexible dosing No food or drink 15 min (Commit Fast nicotine delivery before use Possible mouth soreness, OTC Slow nicotine delivery patch Different strengths available Less flexible dosing (Habitrol Daily application Possible skin irritations Nicoderm Overnight use may reduce Possible sleep problems if CQ early morning cravings worn at night Nicotrol) Nicotine Fastest nicotine delivery Frequent dosing required nasal spray Reduces cravings in minutes Possible nasal and eye (Nicotrol Flexible dosing Irritation, coug Most addictive nicotine replacement therapy Nicotine Flexible dosing Frequent dosing required nhal Mimics hand-to-mouth Possible mouth and throat (Nicotrol routine of smoking Irritation inhaler) Bupropion Non-nicotine Possible insomnia, dry mouth, SR Easy use headache, tremors, nausea (Wellbutrin May be combined with anxiety SR, Zyban) nicotine replacement therapy Avoid use with seizure May delay weight gai In disorders bulimia, anorexia May be effective in depression(see Chapter 13)trauma, current use of bupropion or a monoamine hibi