OH OH C、已 C N C N C N CH HC C HC C N且 N且 Allopurinol Hypoxanthine (enol form) Allopurinol was designed to be a competitive inhibitor of xanthine oxidase to treat gout by Elion and Hitchings who shared the nobel prize in 19 88 for their discoveries of important principles for drug treatmentAllopurinol was designed to be a competitive inhibitor of xanthine oxidase to treat gout by Elion and Hitchings, who shared the Nobel Prize in 1988 for their discoveries of important principles for drug treatment