Chromosomes and DNA Double-stranded DNA Histones are spaced along the DNA double helix at regular intervals the dna itself b g Histone H1 Nucleosome wound around each histone molecule. The packing forms a discrete structure called a nucleosome Nucleosomes aggregate and form a fibrous material called chromatin. Chromatin itself can be compacted by folding and looping to Core histones eventually form an intact oN chromosomeChromosomes and DNA Histones are spaced along the DNA double helix at regular intervals, the DNA itself being wound around each histone molecule. The packing forms a discrete structure called a nucleosome. Nucleosomes aggregate and form a fibrous material called chromatin. Chromatin itself can be compacted by folding and looping to eventually form an intact chromosome