Combretastatins 芳布他汀 ONa CHgO CHaO O=P-ONa 0 CHgO CHgO CHaO CH3O O-P-ONa O-P-ONa CHgO ONa CHgO ONa Combretum caffrum CA1-P granted FDA orphan African Bush Willow drug status for treatment of CA4-P(Zybrestat)granted FDA and EMA orphan Acute Myelogenous drug status for treatment of for treatment of Leukemia (AML).2012) anaplastic thyroid cancer (2003/FDA 2004/EMA) 急性骨髓性白血病 and ovarian cancer (2006/FDA 2013/EMA) 甲状腺癌和卵巢癌 G.Robert Pettit