Functions of the heart umping(泵血) Endocrine(内分泌) Atrial natriuretic peptide(ANP) Other bioactivators Atrial di stenson Sympathetic sti mul ation Angiotensin Il ANp NEP Degradation ↓ Aldosterone 」svR 」c ↓ Renin Arterial Blood Pressureˇ Volume Natriuresis- D Abbreviations: ANP, atrial natriuretic peptide: NEP, neutral peptidase: GFR, glomerular filtration rate CVP, central venous pressure co, cardiac output; SVR, systemic vascular resistanceFunctions of the heart • Pumping（泵血） • Endocrine（内分泌） – Atrial natriuretic peptide (ANP) – Other bioactivators