Individual Proteins are transported within the pattern according to intrinsic signals. Signal sequences ---initiate translocation of proteins across specific membranes. Stop-transfer sequences ---interrupt the translocation process that was previously initiated by a signal sequence. Sorting sequences --act as determinants for posttranslocational traffic of subpopulations of proteins. Insertion sequences -- initiate unilateral integration of proteins into the lipid bilayer without the mediation of a distinct protein effector. --Gunter blobel(PANS Zz, 1980, 1496-1500)# Individual Proteins are transported within the pattern according to intrinsic signals. Signal sequences --- initiate translocation of proteins across specific membranes. Stop-transfer sequences --- interrupt the translocation process that was previously initiated by a signal sequence. Sorting sequences --- act as determinants for posttranslocational traffic of subpopulations of proteins. Insertion sequences --- initiate unilateral integration of proteins into the lipid bilayer without the mediation of a distinct protein effector. ------- Gunter Blobel (PANS 77, 1980, 1496-1500)