ORGANIC CHEMISTRY Chapter 17 C—C-C-R HH B Hydrogens are not acidic a Hydrogens are usually acidic (pKa=40~50 (pKa=19~20) CH3CH3 CH2=CHCH3 (C6H5)2CH2 CH3 CN pl 50 40 32.3 25 CH3SO2CH3 CHsCOCH3 CHINO HH 29 24.7 16.6 17.21 Department of Chemistry, Xiamen UniversityORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 17 C C H C O R H α Hydrogens are usually acidic (pKa = 19 ∼ 20) β Hydrogens are not acidic (pKa = 40 ∼ 50) CH2 CHCH3 pKa H H ~ 50 40 32.3 25 29 24.7 16.6 17.21 CH3CH3 (C6H5)2CH2 CH3CN CH3SO2CH3 C6H5COCH3 CH3NO2