上浒充通大 SHANGHAI JIAO TONG UNIVERSITY 1896 1920 1987 2006 Background Primary effect of diuretics is to increase solute excretion,mainly as NaCl Certain disease states may cause blood volume to increase outside of narrowly defined limits Hypertension Congestive heart failure Liver cirrhosis Nephrotic syndrome Renal failure AO TONG Dietary Na restriction often not enough to prevent edema diuretics neededBackground  Primary effect of diuretics is to increase solute excretion, mainly as NaCl  Certain disease states may cause blood volume to increase outside of narrowly defined limits  Hypertension  Congestive heart failure  Liver cirrhosis  Nephrotic syndrome  Renal failure  Dietary Na restriction often not enough to prevent edema  diuretics needed