Comparing with the fast-response action potential: The resting membrane of slower-response is considerable less negative, a bout -50 mV The slop of the upstroke(phase 0), the amplitude and overshoot of the action potentials are less; (amplitude of action potential and the rate of rise of the upstroke are important determinants of the conduction velocity). 40 Fast response Slow response 0 2 -40 b c ERP RRP 120 ERP 0100200300 100200300 Time(msec)Comparing with the fast-response action potential: The resting membrane of slower-response is considerable less negative, about -50 mV; The slop of the upstroke (phase 0), the amplitude and overshoot of the action potentials are less; （amplitude of action potential and the rate of rise of the upstroke are important determinants of the conduction velocity)