1/17/2016 Control of microbial growth began ~100 years ago Microbes following the discovery that microbes caused disease Lister and Semmelweis were the first to develop microbial control practices-aseptic surgery Invisible Invaders Before that time,10% Amazing Allies of surgical deaths and 25%of delivering mothers deaths were due to infections. During the American Chapter 7 Civil War,a surgeon The Control of Microbial Growth may have cleaned his scalpel on his boot sole between incisions. Terminology of Microbial Control Microbial Control Terminology Sterilization-a process that destroys all living microbes, including viruses and endospores:microbicidal Learning Objectives Commercial sterilization:food is heated enough to destroy endospores of Clostridium botulinum-absolute sterility would degrade the food Define the following key terms related to microbial control: Complete sterilization may not be required in many settings.such as a fork or drinking glass in a restaurant sterilization,disinfection,antisepsis, Aim:to prevent the spread of possible pathogens degerming,sanitization,biocide, Disinfection-a process to destroy vegetative pathogens germicide,bacteriostasis,and asepsis (not endospores)on inanimate objects Antisepsis:disinfectant treatment applied to living tissue Antiseptic:disinfectants applied directly to living tissue 1/17/2016 1 Invisible Invaders Amazing Allies Chapter 7 The Control of Microbial Growth Control of microbial growth began ~100 years ago following the discovery that microbes caused disease Lister and Semmelweis were the first to develop microbial control practices - aseptic surgery Before that time, 10% of surgical deaths and 25% of delivering mothers deaths were due to infections. During the American Civil War, a surgeon may have cleaned his scalpel on his boot sole between incisions. Learning Objectives Terminology of Microbial Control g j Define the following key terms related to microbial control: sterilization, disinfection, antisepsis, degerming, sanitization biocide sanitization, biocide, germicide, bacteriostasis, and asepsis Sterilization – a process that destroys all living microbes, including viruses and endospores; microbicidal Commercial sterilization: food is heated enough to destroy Microbial Control Terminology endospores of Clostridium botulinum - absolute sterility would degrade the food Complete sterilization may not be required in many settings, such as a fork or drinking glass in a restaurant Aim: to prevent the spread of possible pathogens Di i f ti Disinfection – a t d t t ti th process to destroy vegetative pathogens (not endospores) on inanimate objects Antisepsis: disinfectant treatment applied to living tissue Antiseptic: disinfectants applied directly to living tissue