Pathogenicity Enter macrophages and monocytes in pulmonary alveoli Mip protein promotes bacterial adhesion and phagocytosis Form Legionella-containing vacuole and escape from degradation of ysosome Bacteria reproduction Lead to tissue damage and diseases (pneumonia mostly respiratory symptoms)Pathogenicity • Enter macrophages and monocytes in pulmonary alveoli • Mip protein promotes bacterial adhesion and phagocytosis • Form Legionella—containing vacuole and escape from degradation of lysosome • Bacteria reproduction • Lead to tissue damage and diseases (pneumonia mostly: respiratory symptoms)