OH 通过间 H2NSO2 隔基相 CI spacer diuretic B-blocker CH3 药效结构 的拼合 NH2 NH2 Tacrine Huperzine A CH3 石杉碱甲： Tacrine(Cognex®)：treat acetylcholinesterase inhibitor Alzheimer's disease H2N huprines通过间 隔基相 连 H2NSO2 Cl S N N OH O NH O O H H spacer diuretic b-blocker N NH2 H3C CH3 H N O NH2 Tacrine Huperzine A CH3 N H2N 药效结构 的拼合 Tacrine (Cognex ®): treat Alzheimer's disease. 石杉碱甲： acetylcholinesterase inhibitor huprines