KAMARUDDIN ET AL linase Ph 35 Ph (37) n'-PhsCpRu(CO)X.t-BuOK Scheme 14.The DKR of sody lhusing combined uthenu)and lipase catalysis can be used as acyl donors if the alcohol or ketone residuc ess resulted in faster reacti removed tone in % R (38) (39) Yield (% e.e.(%) 469 99 p-MeOC.H m-CF3C&H4 2.Eu n-Hex % /-Bu Methyl phe (40) R R Shvo's catalyst Enzyme con entration Ph Me 0.9 PhOCH 1.0 110 0.5 Scheme 15.The DKR of secndary alohols using allyl esters acyl donors. Chirality DO110.1002/chir can be used as acyl donors if the alcohol or ketone residue formed during the enzymatic acylation was continuously removed during the reaction. The addition of ketone in the racemization process resulted in faster reaction rate and reduced the amounts of enzyme (Novozyme 435) and Shvo’s ruthenium catalyst needed in the process. The Scheme 14. The DKR of secondary alcohols using combined ruthenium (II) and lipase catalysis. Scheme 15. The DKR of secondary alcohols using alkyl esters as acyl donors. 458 KAMARUDDIN ET AL. Chirality DOI 10.1002/chir