Classification of Bilirubin(2) By the type of bilirubin Hyperbilirubinemia mainly by unconjugated rubin Over-produced bilirubin: hemolytic jaundice Bilirubin absorption blocked: Gilbert syndrome Bilirubin conjugation blocked: Gilbert syndrome Hyperbilirubinemia mainly by conjugated bilirubin Post-hepatic obstruction cholelithiasis, cancer of the head of the pancreas Intra-hepatic obstruction; hepatolithiasis Intra-hepatic cholestasis: hepatitis, drugs, infectionClassification of Bilirubin (2) By the type of bilirubin • Hyperbilirubinemia mainly by unconjugated bilirubin Over-produced bilirubin: hemolytic jaundice Bilirubin absorption blocked: Gilbert syndrome Bilirubin conjugation blocked: Gilbert syndrome • Hyperbilirubinemia mainly by conjugated bilirubin Post-hepatic obstruction: cholelithiasis, cancer of the head of the pancreas Intra-hepatic obstruction: hepatolithiasis Intra-hepatic chlolestasis: hepatitis, drugs,infection