CH3 CH CH3 CH3 O H3C Haco N—CH HO O O CH OH H3C O OR CH3 H CH 3 Spiramycin I R= H Spiramycin Il R=COCH 3 Spiramycin Ill R= COCH2 CH3O CH3 OR H3CO H3C O C H O O N CH3 Spiramycin I R = H Spiramycin II CH3 CH3 R = COCH3 Spiramycin III O O CH3 N CH3 H3C O R = COCH2CH3 HO O OH OH CH3 CH3 O