Molecular basis Inflammatory response leads to production and release of a number of chemical effectors of inflammation responsible for vascular permeability vasodilation, and pain Histamine Kinin Leukotrienes and prostaglandins BIOL 533 Lecture 5BIOL 533 11 Lecture 5 Molecular Basis • Inflammatory response leads to production and release of a number of chemical effectors of inflammation responsible for vascular permeability, vasodilation, and pain – Histamine – Kinin – Leukotrienes and prostaglandins