BEH.462/3. 962J Molecular Principles of Biomaterials Spring 2003 Plate-like aragonite( CaCO3) crystals form the inner layer of seashells: ( scale 6.38 Structural model for geometric matching in shel nacre. R, 6.39 Role of IAsp-XI domains in Ca"binding and oriented nucleation in shell nacr Biomimetic organic templated materials Patterned surface mimics of templated inorganics Directed mineral deposition by patterned surfaces presenting organized charged groups2 Work of Joanna Aizenberg at Bell Labs °Neh2p HS(CH2)2OH on Au (Ca1210 mM: N= 100 (Ca-1=10 mM. N =100 PDMS stamps with anous relief structures th HS(CH2)isCO2H Nucleating plane (012) Nucleating plane(01 Microcontact print HS(CH2)15CO2H Ca"=10 mM: N= 100 ca21=100mMN=10.000 CO,H-terminated SAM Wash with HS(CH?)sCH3 CHa-terminated SAM =10m crystallization solution HSC.DH, The density and tim d batres n the tno an the ATm wh wanou oates d aceton N-100"nem and 以以以 PDMS supports Boomed o AfHL c Amys df ortet wth ne ceret a ragmensinght wow he tomson d urmoemen 33sof.om (Aizenberg et al. 2000) Lecture 12-Inorganic biomaterials 5of13BEH.462/3.962J Molecular Principles of Biomaterials Spring 2003 Plate-like aragonite (CaCO3) crystals form the inner layer of seashells: (scale bar 1 µm) Biomimetic organic templated materials Patterned surface mimics of templated inorganics1 Directed mineral deposition by patterned surfaces presenting organized charged groups2,3 ƒ Work of Joanna Aizenberg at Bell Labs: (Aizenberg et al. 2000) Lecture 12 – Inorganic Biomaterials 5 of 13