4)Pathologic acid-hypersecretory conditions(e.g. Zollinger-Ellison syndrome) Tumor Gastrin Gastic acid zollinger- Ellison tumor In pancreas Peptic ulcer Duodenal ulcers due to hyperacidity 9 ADAM Ine4) Pathologic acid-hypersecretory conditions (e.g. Zollinger-Ellison syndrome) Tumor Gastrin Gastic acid Peptic ulcer