General properties of Macrolides 1. Antimicrobial spectrum Gt organisms G- cocci: Streptococcus pyogenes and pneumoniae Mycoplasma pneumoniae(肺支原体)and Legionnella(军团菌)etc 2. Antimicrobial activity: bactericidal and bacteriostatic depending on the concentration · more active at alkaline1. Antimicrobial spectrum： • G+ organisms • G- cocci: Streptococcus pyogenes and pneumoniae • Mycoplasma pneumoniae(肺支原体) and Legionnella (军团菌)etc. 2. Antimicrobial activity: • bactericidal and bacteriostatic, depending on the concentration. • more active at alkaline General properties of Macrolides