Epitope 2 Anti-Epitope 1 Anti-Epitope 2 Epitope Characteristics The paratope of an antibody that is specific for an antigen binds noncovalently to a region of the molecule know as the epitope.Naturally occurring epitopes are relatively small about four to six amino acids or sugar residues.The convex epitope area might be only 2 X 3 nm across.At these dimension epitopes can fit into the antigen binding site (paratope)of the antibody. -Epitope -Paratope (Atigen binding site) ntigen Antibody Ag and Ab Comi Large antigens (proteins or other macromoleculse)can possess many different epitopes on the it could stimula at antigen binding site (paratope)is concave pocket which match the convexity of the epitope.The paratope and epitope must come in close contact with each other since the binding forces are short (4 A)and weak. Epitope Characteristics The paratope of an antibody that is specific for an antigen binds noncovalently to a region of the molecule know as the epitope. Naturally occurring epitopes are relatively small about four to six amino acids or sugar residues. The convex epitope area might be only 2 X 3 nm across. At these dimension epitopes can fit into the antigen binding site (paratope) of the antibody. Large antigens (proteins or other macromoleculse) can possess many different epitopes on the same molecule. If an antigens has four different epitopes it could stimulate the production of four different antibody molecules with different paratopes. The antigen binding site (paratope) is concave pocket which match the convexity of the epitope. The paratope and epitope must come in close contact with each other since the binding forces are short (4 A) and weak