Antigens The cause of immunologically mediated renal disease is antigenic triggering of an immune reaction The list of associated antigens is extensive and continually expanding. These antigens are categorized as renal or non-renal and as self or foreign The causative antigen is often unknown• The cause of immunologically mediated renal disease is antigenic triggering of an immune reaction. • The list of associated antigens is extensive and continually expanding. These antigens are categorized as renal or non-renal and as self or foreign . • The causative antigen is often unknown. Antigens