Reactions of Amines Biological eliminations analogous to the Hofmann elimination occur frequently In the biosynthesis of nucleic acids adenylosuccinate undergoes elimination of a positively charged nitrogen to give fumarate plus adenosine monophosphate B H C02 020 H +NH2 NH2 Adenylosuccinate Fumarate Adenosine monophosphate▪ Biological eliminations analogous to the Hofmann elimination occur frequently ▪ In the biosynthesis of nucleic acids adenylosuccinate undergoes elimination of a positively charged nitrogen to give fumarate plus adenosine monophosphate Reactions of Amines