Medical Genetics You should consider genetic counseling if any of the following risk factors apply to you: 1 if a standard prenatal screening test (such as the alpha fetoprotein test)yields an abnorma result (2) if an amniocentesis yields an unexpected result(such as a chromosomal defect in the unborn baby)Medical Genetics You should consider genetic counseling if any of the following risk factors apply to you: (1) if a standard prenatal screening test (such as the alpha fetoprotein test) yields an abnormal result (2) if an amniocentesis yields an unexpected result (such as a chromosomal defect in the unborn baby)