冬蛋白分选：蛋白分子在蛋白内部的分选信号指导下从细 胞质运往各种目标细胞器或细胞表面。 TABLE 12-3 Some Typical Signal Sequences FUNCTION OF SIGNAL SEQUENCE EXAMPLE OF SIGNAL SEQUENCE Import into nucleus -Pro-Pro-Lys-Lys-Lys-Arg-Lys-Val- Export from nucleus -Leu-Ala-Leu-Lys-Leu-Ala-Gly-Leu-Asp-Ile- Import into mitochondria +HaN-Met-Leu-Ser-Leu-Arg-GIn-Ser-Ile-Arg-Phe-Phe-Lys-Pro-Ala-Thr-Arg-Thr- Leu-Cys-Ser-Ser-Arg-Tyr-Leu-Leu- Import into plastid +HaN-Met-Val-Ala-Met-Ala-Met-Ala-Ser-Leu-GIn-Ser-Ser-Met-Ser-Ser-Leu-Ser- Leu-Ser-Ser-Asn-Ser-Phe-Leu-Gly-GIn-Pro-Leu-Ser-Pro-lle-Thr-Leu-Ser-Pro- Phe-Leu-GIn-Glv- Import into peroxisomes -Ser-Lys-Leu-COO- Import into ER +H2N-Met-Met-Ser-Phe-Val-Ser-Leu-Leu-Leu-Val-Gly-Ile-Leu-Phe-Trp-Ala-Thr- Glu-Ala-Glu-GIn-Leu-Thr-Lys-Cys-Glu-Val-Phe-GIn- Return to ER -Lvs-Asp-Glu-Leu-COO Some characteristic features of the different classes of signal sequences are highlighted in color.Where they are known to be important for the function of the signal seqquence,positively charged amino acids are shown in red and negatively charged amino acids are shown in green.Similary,important hydrophobic arino acids are shown in yellow and hydroxylated amino acids are shown in blue.+H3N indicates the N-teminus of a protein;COO indicates the C-terminus. 冬没有任何信号肽（序列）的蛋白是细胞质基质驻留蛋白。❖蛋白分选: 蛋白分子在蛋白内部的分选信号指导下从细 胞质运往各种目标细胞器或细胞表面。 ❖没有任何信号肽（序列）的蛋白是细胞质基质驻留蛋白