What forces determine the structure? Primary structure determined by covalent bonds Secondary, tertiary, Quaternary structures all determined by weak forces Weak forces -hbonds. ionic interactions van der waals interactions, hydrophobic interactionsWhat forces determine the structure? • Primary structure - determined by covalent bonds • Secondary, Tertiary, Quaternary structures - all determined by weak forces • Weak forces - H-bonds, ionic interactions, van der Waals interactions, hydrophobic interactions