The Pathogen Five major species of Schistosoma affect humans: s. mansonis haematobium. s japonicum, S intercalatum, and S. mekongi Other Schistosoma species that occasionally infect humans include s. bovis.s. mattheei and some avian schistosomesThe Pathogen  Five major species of Schistosoma affect humans: S. mansoni, S. haematobium, S. japonicum, S. intercalatum, and S. mekongi.  Other Schistosoma species that occasionally infect humans include S. bovis, S. mattheei, and some avian schistosomes