Question#34 Which of the following statements is true for calcitonin-secreting cells? A they secr te calcitonin in B they are located either in the walls of follieles or in the interstitiu botween follicles C.they regulate thyroglobulin production in follicular cells D.they contain abundant smooth endoplasmic reticulum E.cancers involving these cells are unknown Thyroid stimulating hormone (TSH)stimulates which of the following processes in thyroid follicular cells? A.uptake of iodide from the blood plasma B.synthesis of thyroglobulin C.iodination of thyroglobui D.endocytosis of thyroglobulin E.all of the above Question #36 Patientsith Graves'disease are hyperthyroid,mostly resulting froa the production of circulating antibodies that structurally resemble TSH(thyroid stimulating hornone or thyrotropin)and can bind and activate the TSH receptor.Which one of the following likely characterizes their plasma levels of thyroxine (T4)and TSH? A high T4 and lo TSH B.high T4.and high TSH C.low T4 and high TS D.low T4 and low TSH Question#37 Peptide hormones are produced exclusively in specialized endocrine glands B.are mostly secreted as inactive precursors and are activated by target tissues C.can be stored in the same intracellular organelles as biogenic amines such as epinephrine D.are cleared slowly from the circulation after secretion and thus remain effective for hours E.translocate across the plasma membranes of target cells and bind to cytoplasaic receptors Vasopressin but not ACTH(adrenocorticotropic hormone) A requires enzymes located in nitochondria for its synthesis B.is produced by processing of a high molecular weight hormone precursor C.undergoes axonal transport before secretionQuestion # 34 Which of the following statements is true for calcitonin-secreting cells? A. they secrete calcitonin in response to low serum calcium B. they are located either in the walls of follicles or in the interstitium between follicles C. they regulate thyroglobulin production in follicular cells D. they contain abundant smooth endoplasmic reticulum E. cancers involving these cells are unknown -------------------------------------------------------------------------------- Question # 35 Thyroid stimulating hormone (TSH) stimulates which of the following processes in thyroid follicular cells? A. uptake of iodide from the blood plasma B. synthesis of thyroglobulin C. iodination of thyroglobulin D. endocytosis of thyroglobulin E. all of the above -------------------------------------------------------------------------------- Question # 36 Patients with Graves' disease are hyperthyroid, mostly resulting from the production of circulating antibodies that structurally resemble TSH (thyroid stimulating hormone or thyrotropin) and can bind and activate the TSH receptor. Which one of the following likely characterizes their plasma levels of thyroxine (T4) and TSH? A. high T4 and low TSH B. high T4, and high TSH C. low T4 and high TSH D. low T4 and low TSH -------------------------------------------------------------------------------- Question # 37 Peptide hormones A. are produced exclusively in specialized endocrine glands B. are mostly secreted as inactive precursors and are activated by target tissues C. can be stored in the same intracellular organelles as biogenic amines such as epinephrine D. are cleared slowly from the circulation after secretion and thus remain effective for hours E. translocate across the plasma membranes of target cells and bind to cytoplasmic receptors -------------------------------------------------------------------------------- Question # 38 Vasopressin but not ACTH (adrenocorticotropic hormone) A. requires enzymes located in mitochondria for its synthesis B. is produced by processing of a high molecular weight hormone precursor C. undergoes axonal transport before secretion