Nucleotides and Nucleic Acids Nucleotides are linked together in DNA and RNA by phosphodiester bonds between the phosphate group at C5'on one nucleotide and the 3'-hydroxyl group of the sugar of another nucleotide C3'is one free hydroxyl group at the end of the nucleic polymer (the 3'end) C5'is another free hydroxyl group at the other end of the nucleic polymer (the 5'end) Sequence of nucleotides in a chain is described by starting at the 5'end and identifying the bases in order of occurrence(using G,C,A,T or U) 5end 5'end 日ase O=POCH Phosphate Sugar Base Phosphate Sugar Base 3'end 3end ▪ Nucleotides are linked together in DNA and RNA by phosphodiester bonds between the phosphate group at C5′ on one nucleotide and the 3′-hydroxyl group of the sugar of another nucleotide ▪ C3′ is one free hydroxyl group at the end of the nucleic polymer (the 3′ end) ▪ C5′ is another free hydroxyl group at the other end of the nucleic polymer (the 5′ end) ▪ Sequence of nucleotides in a chain is described by starting at the 5′ end and identifying the bases in order of occurrence (using G, C, A, T or U) Nucleotides and Nucleic Acids