Systemic Edema Drug-induced edema Renal vasoconstriction (NASID, cyclosporine) Arterial dilatation(vasodilators Augmented renal sodium reabsorption (steroid hormone) Capillary damage (interleukin-2)Systemic Edema Drug - induced Edema • Renal vasoconstriction (NASID, cyclosporine) • Arterial dilatation (vasodilators) • Augmented renal sodium reabsorption (steroid hormone) • Capillary damage (interleukin-2)