Epidemiology Incidence: 1 in 1. 000-10.000 Female to male ratio: 9-1 More common in African-Americans but it affects all races Mean age of onset: 28 years Positive family history in 10-15% of patients Monozygotic twins exhibit a greater rate of concordance(24%)than dizygotic twins(1-3%) The risk of a child developing lupus born from a mother (or father) with lupus is calculated to be 3-4% at worstEpidemiology • Incidence: 1 in 1,000 -10,000 • Female to male ratio: 9-1 • More common in African-Americans but it affects all races • Mean age of onset: 28 years • Positive family history in 10 -15% of patients • Monozygotic twins exhibit a greater rate of concordance (24%) than dizygotic twins (1-3%) • The risk of a child developing lupus born from a mother (or father) with lupus is calculated to be 3-4% at worst