16.3 Retroviruses may transduce cellular sequences Figure 16.11 Replication- Provirus C-onc dene LTR gag pof eny LTR Exon Intron Exon defective viruses may be MaM enerated through DELETION integration and deletion of Maw A. a viral genome to generate Transcription tom Transcription from a fused viral-cellular deleted provirus another provirus transcript that is packaged with a normal rna genome. Nonhomologous recombination is P ackaging into virion necessary to generate the replication-defective RNA recom bination transforming genome 请莘大Figure 16.11 Replication￾defective viruses may be generated through integration and deletion of a viral genome to generate a fused viral-cellular transcript that is packaged with a normal RNA genome. Nonhomologous recombination is necessary to generate the replication-defective transforming genome. 16.3 Retroviruses may transduce cellular sequences