haracteristics ch 1. Graded dose-dependent depression of cNs function Coma g Anesthesia 000z0 Drug B enosIs Sedation Increasing dose Dose-response curves for two hypothetical sedative-hypnotics Drug A: barbiturates Drug B: benzodiazepines and certain newer hypnotics7 1. Graded dose-dependent depression of CNS function Characteristics Dose-response curves for two hypothetical sedative-hypnotics Drug A: barbiturates Drug B: benzodiazepines and certain newer hypnotics