1. Acid-peptic disorders 1) Peptic ulcer disease(PUD,消化性溃疡) 2) Gastroesophageal reflux disease GErD) 3)Drug-induced mucosal injury, especially by non-steroidal anti-inflammatory drugs NSAids) 4)Pathologic acid-hypersecretory conditions(e.g Zollinger-Ellison syndrome) 5)Acute stress ulcers1. Acid-peptic disorders 1) Peptic ulcer disease (PUD, 消化性溃疡) 2) Gastroesophageal reflux disease (GERD) 3) Drug-induced mucosal injury, especially by non-steroidal anti-inflammatory drugs (NSAIDs) 4) Pathologic acid-hypersecretory conditions (e.g. Zollinger-Ellison syndrome) 5) Acute stress ulcers