2.Transmembrane signal transduction Concept ●Several main forms Mediated by ion channel Mediated by G-protein coupled receptor Mediated by tyrosine kinase receptor Mediated by intercellular channel Mediated by nitric oxide Cellular proto-oncogene Mediate-early gene§ 2. Transmembrane signal transduction • Concept • Several main forms * Mediated by ion channel * Mediated by G-protein coupled receptor * Mediated by tyrosine kinase receptor * Mediated by intercellular channel * Mediated by nitric oxide • Cellular proto-oncogene Mediate-early gene