PATHOGENY AND PATHOGENESIS(4) 6 inflammatory media theory In AP, the leukocytes that appear first in areas of inflammation are neutrophils, then macrophages, monocytes, lymphocytes and other cells. These cells can secrete a lot of inflammatory media (1)platelet activating factor, PAF 2)prostaglandins, PGs8 PATHOGENY AND PATHOGENESIS(4) 6 inflammatory media theory In AP, the leukocytes that appear first in areas of inflammation are neutrophils, then macrophages, monocytes, lymphocytes, and other cells. These cells can secrete a lot of inflammatory media. (1) platelet activating factor, PAF (2)prostaglandins, PGs