012-3-11 Definition Urinary Tract a Urinary tract infections are acute Infections(UTIs) chronic inflammatory reactions caused by proliferation of pathogenic microorganisms Tongying Zhu existing in the urinary tract Huashan Hospital Fudan Definition(cont Classification of utis a Infections of the urinary tract can be subdivided into two general anatomic Asymptomatic bacteriuria Symptoms O Lower tract infection(urethritis and cystitis radic(sI UT1/6 mo and s2 UTIs/yr) a Upper tract infection(pyelonephritis, intrarenal Recurrent(22 UTIs/ 6 mo or 23 UTls/yr) and perinephric abscesses) Reinfection Complicating factors Complicated(see text UTl=urinary tract infection. Epidemiology Epidemiology(cont s Worldwide, at least 150 million cases of symptomatic UTIs who have utis is lower nales, who are also more likely to hav number of cases ymptomatic bacteriuria. a 90% of patients have cystitis and 10% have pyelonephritis (short urethra, also be the result of sexual abuse n Sporadic in about 70% of patients and recurrent in 25%. m In young man under 50, UTIs are rare and are often the result n About 2% have complicated infections related to factors that of underlying infections of the prostate. tic and asymptomatic UTIs erity are included, the Women often the result of atrophic vagin equency of complicated infections is about 8%. ence of prostate hyperplasia or cancer.2012-3-11 1 Urinary Tract Infections(UTIs) Tongying Zhu Huashan Hospital Fudan University Definition „ Urinary tract infections are acute or chronic inflammatory reactions caused by proliferation of pathogenic microorganisms existing in the urinary tract. Definition(cont.) „ Infections of the urinary tract can be subdivided into two general anatomic categories: …Lower tract infection (urethritis and cystitis) …Upper tract infection (pyelonephritis, intrarenal and perinephric abscesses) Classification : Table 292-1 Classification of UTIs Epidemiology „ Worldwide, at least 150 million cases of symptomatic UTIs occur each year. „ The number of patients who have UTIs is lower than the number of cases. „ 90% of patients have cystitis and 10% have pyelonephritis 90% of patients have cystitis and 10% have pyelonephritis. „ Sporadic in about 70% of patients and recurrent in 25%. „ About 2% have complicated infections related to factors that increase the risk of establishment and management of bacteriuria. „ If factors that can increase the severity are included, the frequency of complicated infections is about 8%. Epidemiology (cont.) „ In very young child, UTIs more common in boy. „ Later in childhood and adult, symptomatic UTIs are more common in females, who are also more likely to have asymptomatic bacteriuria. (short urethra also be the result of sexual abuse) (short urethra, also be the result of sexual abuse) „ In young man under 50, UTIs are rare and are often the result of underlying infections of the prostate. „ In elderly people, both symptomatic and asymptomatic UTIs are common. … Women: often the result of atrophic vaginal mucosa … Men: often the consequence of prostate hyperplasia or cancer