DNA gel mobility(DNA在胶上的迁移性 1.DNA and RNA molecules are negatively charged, thus move in the gel matrix(胶支持物) toward the positive pole(正电极) 2. Linear DNA molecules are separated according to sizes. The large dna molecules move slower than the small molecules 3. The mobility of circular DNA molecules is affected by their topological structures. The mobility of the same molecular weight DNA molecule with different shapes is: supercoiled(超螺旋)> linear(线性)> nicked or relaxed(缺刻或松散)8 1.DNA and RNA molecules are negatively charged, thus move in the gel matrix (胶支持物) toward the positive pole (正电极). 2.Linear DNA molecules are separated according to sizes. The large DNA molecules move slower than the small molecules. 3.The mobility of circular DNA molecules is affected by their topological structures. The mobility of the same molecular weight DNA molecule with different shapes is: supercoiled (超螺旋)> linear (线性) > nicked or relaxed (缺刻或松散) DNA gel mobility (DNA在胶上的迁移性)