PhOCH,C CH CH COOH Amides acylated. inactive enzyme Product of the reaction of a carboxylic acid and ammonia or an amine. Not basic because the lone pair on nitrogen is delocalized by resonance. :O: :0: H H H H Bond angles around N are close to120°. => Chapter 21 6Chapter 21 6 Amides • Product of the reaction of a carboxylic acid and ammonia or an amine. • Not basic because the lone pair on nitrogen is delocalized by resonance. H C O N H H H C O N H H _ + Bond angles around N are close to 120. =>