Y一 - NH2 H2o=Y -NH3 +Oh Stronger Substituents, Y pKa base -NH 2 6.15 OH534 Activating CH roups 508 4.63 Cl 3.98 ①D Br 3.86 Deactivating C≡N1.74gru ps 可 Weaker NO 1.00 baseOrganic Chemistry Organic Chemistry Xiamen Xiamen University University NH 2 OH CH 3 H Cl Br C N NO 2 6.15 5.34 5.08 4.63 3.98 3.86 1.74 1.00 A ctiv atin g groups De a ctiv atin g gr o up s S ub stitu e nts, Y pK a Y NH 2 + H 2 O Y NH 3 + O H Stronger base Weaker base