Treatment Elimination enhancement Alkaline diuresis enhances elimination of phenobarbital and other long-acting barbiturates It is recommended for all symptomatic patients with long-acting barbiturate toxicity. Consider hemodialysis or hemoperfusion in glutethimide, methyprylon phenobarbital meprobamate and chloral hydrate poisoning◼ Elimination enhancement ◼ Alkaline diuresis enhances elimination of phenobarbital and other long-acting barbiturates. It is recommended for all symptomatic patients with long-acting barbiturate toxicity. ◼ Consider hemodialysis or hemoperfusion in glutethimide, methyprylon, phenobarbital, meprobamate, and chloral hydrate poisoning. Treatment