3/13/2016 Vibrio cholerae HOW IT SPREADS virulence mechanisms Produces a number of other extracellular toxins that are harmful to the host cells Other virulence factors Flagella,LPS,capsule,colonization factors Vibrio mimicus Vibrio mimicus foodborne outbreaks Known as the sucrose-negative V.cholerae ·Gasteroenteritis Distinctly different to V cholerae based on biochemical tests Associated only with consumption of seafood Causes gastroenteritis and may cause ear infections In US,raw oysters mainly Reservoir:aquatic environment ·In Japan,raw fish Free in the water Associated with roots of aguatic plants and plankton(60,000 CFU per gram) 10 3/13/2016 10 Vibrio cholerae virulence mechanisms • Produces a number of other extracellular toxins that are harmful to the host cells • Other virulence factors • Flagella, LPS, capsule, colonization factors Vibrio mimicus • Known as the sucrose-negative V. cholerae • Distinctly different to V cholerae V. cholerae based on based on biochemical tests • Causes gastroenteritis and may cause ear infections • Reservoir: aquatic environment - Free in the water - Associated with roots of aquatic plants and plankton (60,000 CFU per gram) Vibrio mimicus foodborne outbreaks • Gasteroenteritis • Associated only with consumption of seafood • In US, raw oysters mainly • In Japan, raw fish