Mar.Drugs 2014,12 259 liposomal doxorubicin in 2009,but the corresponding U.S.FDA (Food and Drug Administration) application was withdrawn. Figure 2.Approved marine-derived drugs and close analogues in clinical trials 4.Cytarabine(Cytosar(R) 6.PM-10450(ZalypsisR) rabectedin (Yondelis 8.Eribulin (Halaven(R) 7.PM-01183(Lurbinectedin) ga,P 9.Brentuximab vedotin(AdcetrisR) 10.Monomethylauristatin E(Vedotin 11.Monomethylauristatin FMar. Drugs 2014, 12 259 liposomal doxorubicin in 2009, but the corresponding U.S. FDA (Food and Drug Administration) application was withdrawn. Figure 2. Approved marine-derived drugs and close analogues in clinical trials