Control of Gene Expression Transcription factor binding sites are found within larger functional units of the dNa called cis-regulatory elements There are two main type of cis-regulatory elements: promoters and cis-regulatory modules(sometimes calledenhancers) cis-regulatory module( CRM) TFBS Transcription factor binding site(TFBS) TFBS activators DNA O coactivator neral transcription ors RNA polymerase TATA box coding region RNA transcript Department of Biochemistry Molecular Biology eDepartment of Biochemistry & Molecular Biology 4 Control of Gene Expression Transcription factor binding sites are found within larger functional units of the DNA called cis-regulatory elements. There are two main type of cis-regulatory elements: promoters, and cis-regulatory modules (sometimes called “enhancers”). TFBS TFBS transcription factor binding site (TFBS) cis-regulatory module (CRM)