Cpg Island Hidden Markov Model P:=0.001 g P=0.99999 P:=0999 Genome Hidden Pn:=0.00001 Island ↓↓↓↓↓↓↓↓ A C T C GA G T A C G A T Observable CpG Island: 0.3 0.3 0.2 0.2 Genome:02020.30.3Hidden CpG Island Hidden Markov Model P Pig = 0.001 P = 0.99999 gg ii = 0.999 Genome Pgi = 0.00001 Island … A C T C G A G T A CpG Island: C 0.3 G 0.3 A 0.2 T 0.2 Genome: 0.2 0.2 0.3 0.3 Observable