Carrier proteins bind one or more solute molecules on one side of the membrane and then undergo a conformational change that transfer the solute to the other side of the membrane solute lipid pong ing bilayer OUTSIDE ④④ electrochemical gradient INSIDE carrier protein mediating facilitated diffusion❖Carrier proteins bind one or more solute molecules on one side of the membrane and then undergo a conformational change that transfer the solute to the other side of the membrane