Organic Chemistry with BiologicalApplications.3Edition John McMurry Hdomework:P434c:12.42a-912.44:12.51: P434g:12.62:12.67:12.74 Key Notes Nucleophilic Substitution,SN1/SN2,Elimination(E1/E2) Nucleophilicity,Leaving group ethyl bromide (1) isopropyl bromide (2) t-butyl bromide(3°) attack is easy attack is possible attack is impossible HO:CH3 HO:CH3 HO: -Br -Br H H3C H Organic Chemistry with Biological Applications, 3 rd Edition John McMurry Key Notes Nucleophilic Substitution, SN1/SN2, Elimination（E1/E2） Nucleophilicity, Leaving group Homework： P434c: 12.42a-g; 12.44; 12.51; P434g:12.62; 12.67;12.74;