Early congenital syphilis 1.skin and mucous membrane lesions -most cases occur within the first three weeks of life -The typical eruption is maculo- papular and consists of small spots that are dark red to copper. -A classic mucocutaneous sign is depressed linear radiating from the orifice of the mouthEarly congenital syphilis 1. skin and mucous membrane lesions - most cases occur within the first three weeks of life - The typical eruption is maculopapular and consists of small spots that are dark red to copper. - A classic mucocutaneous sign is depressed linear radiating from the orifice of the mouth