Nw.cab.zju.edu.cn/cab/ xueyuanxiashubumen/nx/ bioinplant.htm《生物信息学札记》樊龙江 Analysis of the codons used in a particular gene or organism coG(直系同源簇) Clusters of orthologous groups in a set of groups of related sequences in microorganism and yeast(S. cerevisiae). These groups are found by whole proteome comparisons and include orthologs and paralogs. See also Orthologs and Paralogs Comparative genomics(比较基因组学) A comparison of gene numbers, gene locations, and biological functions of genes in the genomes of diverse organisms, one objective being to identify groups of genes that play a unique biological role in a particular organism Complexity( of an algorithm)(算法的复杂性) Describes the number of steps required by the algorithm to solve a problem as a function of the amount of data; for example, the length of sequences to be aligned Conditional probability(条件概率) The probability of a particular result (or of a particular value of a variabl given one or more events or conditions(or values of other variables Conservation(保守) Changes at a specific position of an amino acid or(less commonly, DNA) sequence that preserve the physico-chemical properties of the original residue Consensus(一致序列) A single sequence that represents at each subsequent position, the variation found within corresponding columns of a multiple sequence alignment Context-free grammars A recursive set of production rules for generating patterns of strings. These consist of a set of terminal characters that are used to create strings, a set of nonterminal symbols that correspond to rules and act as placeholders for patterns that can be generated using terminal characters, a set of rules for replacing nonterminal symbols with terminal characters, and a start symbol Contig(序列重叠群/拼接序列 A set of clones that can be assembled into a linear order. A DNA sequence that overlaps with another contig. The full set of overlapping sequences (contigs)can be put together to obtain the sequence for a long region of DNA that cannot be sequenced in one run in a sequencing assay. Important in genetic mapping at the molecular level CORBA(国际对象管理协作组制定的使OOP对象与网络接口统一起来的一套跨 计算机、操作系统、程序语言和网络的共同标准) The Common object Request Broker Architecture (CORBA)is an open industry standard for working with distributed objects, developed by the object Management Group. CORBA allows the interconnection of objects and applications regardless of computer language, machine architecture, oI geographic location of the computers Correlation coefficient(相关系数)www.cab.zju.edu.cn/cab/xueyuanxiashubumen/nx/bioinplant.htm 《生物信息学札记》 樊龙江 Analysis of the codons used in a particular gene or organism. COG（直系同源簇） Clusters of orthologous groups in a set of groups of related sequences in microorganism and yeast (S. cerevisiae). These groups are found by whole proteome comparisons and include orthologs and paralogs. See also Orthologs and Paralogs. Comparative genomics（比较基因组学） A comparison of gene numbers, gene locations, and biological functions of genes in the genomes of diverse organisms, one objective being to identify groups of genes that play a unique biological role in a particular organism. Complexity (of an algorithm)（算法的复杂性） Describes the number of steps required by the algorithm to solve a problem as a function of the amount of data; for example, the length of sequences to be aligned. Conditional probability（条件概率） The probability of a particular result (or of a particular value of a variable) given one or more events or conditions (or values of other variables). Conservation （保守） Changes at a specific position of an amino acid or (less commonly, DNA) sequence that preserve the physico-chemical properties of the original residue. Consensus（一致序列） A single sequence that represents, at each subsequent position, the variation found within corresponding columns of a multiple sequence alignment. Context-free grammars A recursive set of production rules for generating patterns of strings. These consist of a set of terminal characters that are used to create strings, a set of nonterminal symbols that correspond to rules and act as placeholders for patterns that can be generated using terminal characters, a set of rules for replacing nonterminal symbols with terminal characters, and a start symbol. Contig （序列重叠群/拼接序列） A set of clones that can be assembled into a linear order. A DNA sequence that overlaps with another contig. The full set of overlapping sequences (contigs) can be put together to obtain the sequence for a long region of DNA that cannot be sequenced in one run in a sequencing assay. Important in genetic mapping at the molecular level. CORBA（国际对象管理协作组制定的使OOP对象与网络接口统一起来的一套跨 计算机、操作系统、程序语言和网络的共同标准） The Common Object Request Broker Architecture (CORBA) is an open industry standard for working with distributed objects, developed by the Object Management Group. CORBA allows the interconnection of objects and applications regardless of computer language, machine architecture, or geographic location of the computers. Correlation coefficient（相关系数） 129